Agranulocytotic angina

Introduction

Introduction to granulocytic leukemia Granulocyte deficiency is a systemic disease, and this disease is often accompanied by pharyngeal ulcer disease, called granulocytolytic angina. There are many reasons for this disease, which can be divided into congenital or acquired acquiredness. It can also be divided into five categories according to the reduction of granulocyte production, ineffective proliferation, excessive destruction, compound causes and pseudo-granulocytopenia. Side effects, such as chloramphenicol, indomethacin, etc. or side effects of radioactive substances, can inhibit bone marrow, affect hematopoietic function and reduce granulocytes, or even completely disappear; splenomegaly, hypersplenism, can cause granulocyte destruction, adult And the absolute value of granulocytes in the blood around children is less than 1500 × 106 / L, you can diagnose neutropenia. basic knowledge The proportion of illness: 0.02% Susceptible people: no special people Mode of infection: non-infectious Complications: pneumonia

Cause

Causes of granulocytic leukemia

There are many reasons for this disease, which can be divided into congenital or acquired acquiredness. It can also be divided into five categories according to the reduction of granulocyte production, ineffective proliferation, excessive destruction, compound causes and pseudo-granulocytopenia. Side effects, such as chloramphenicol, indomethacin, etc. or side effects of radioactive substances, can inhibit bone marrow, affect hematopoietic function and reduce granulocytes, or even completely disappear; splenomegaly, hypersplenism, can cause granulocyte destruction, adult And the absolute value of granulocytes in the blood around children is less than 1500 × 106 / L, you can diagnose neutropenia.

Prevention

Granulocyte deficiency angina prevention

The disease is an infectious disease, and the preventive measures should be carried out on the patient's physique. It is usually seen in people with low physical fitness and normal colds. Therefore, it is usually necessary to exercise more. Eat more fruits and vegetables rich in vitamin C, which can reduce the income. The chance of illness. For patients who have already contracted this disease, they should be actively treated to reduce the incidence of complications.

Complication

Granulocytic leukemia complication Complications pneumonia

The disease belongs to leukocyte deficiency, and it can affect the defense function of the body for severe granulocyte deficiency. Therefore, it can induce serious infections of the whole body, including sepsis and sepsis. As angina can also spread to surrounding tissues, causing infections in surrounding tissues, such as eustachian tube infections, resulting in obstruction of the eustachian tube leading to complications such as tinnitus.

Symptom

Granulocyte-deficient angina symptoms common symptoms granulocytopenia sore throat high fever dysphagia

According to the history of systemic diseases of neutropenia and related test results, combined with the characteristics of local symptoms and pharyngeal lesions, the diagnosis can be confirmed.

Because granulocytopenia is easy to secondary infection, the general condition is very poor, accompanied by high fever, sore throat, difficulty in swallowing, bad breath and other symptoms. The pharyngeal examination shows that the mucous membrane of the tonsil, zygomatic arch, soft palate, etc. is necrotic and ulcerated, covered with dark brown false. Membrane, oral mucosa and gums have similar lesions, and the disease develops rapidly. Later, sepsis symptoms and pneumonia can occur.

Examine

Examination of granulocytic leukemia

The pharyngeal examination showed that the mucosa of the tonsils, zygomatic arch, soft palate, etc. was necrotic and ulcerated, covered with a dark brown pseudomembrane, and the oral mucosa and gums had similar lesions.

Diagnosis

Diagnosis and diagnosis of granulocytic leukemia

According to the history of systemic diseases of neutropenia and related test results, combined with the characteristics of local symptoms and pharyngeal lesions, the diagnosis can be confirmed.

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