Gallbladder carcinoid
Introduction
Introduction to gallbladder carcinoid Carcinoid is a relatively rare endocrine tumor derived from kultchitsky cells of neuroendocrine tissue. It accounts for about 2% of all digestive tract tumors. basic knowledge The proportion of illness: 0.005% Susceptible people: no special people Mode of infection: non-infectious complication:
Cause
Causes of gallbladder carcinoid
(1) Causes of the disease
Carcinoid is a relatively rare endocrine tumor, derived from kultchitsky cells of neuroendocrine tissue. Gallbladder carcinoids occur mostly at the bottom of the gallbladder.
(two) pathogenesis
Gallbladder carcinoids occur mostly at the bottom of the gallbladder. The appearance of carcinoid tissue is pale yellow. It is brown after being fixed by formaldehyde. The texture is firm and the cut surface is homogeneous. Under the microscope, the tumor cells are small, polygonal, and medium-sized. The syrup is mildly basophilic, with argyrophilic granules and lipid-containing vacuoles, and the granules contain serotonin.
Prevention
Gallbladder carcinoid prevention
prevention:
1. Maintain a happy state of mind, develop good eating habits, fast food, eat less thick food, do not drink hard alcohol.
2. For people over the age of 40, especially women, regular B-ultrasound examination, found cholecystitis, gallstones or polyps, etc., should be followed up and found that changes in the condition should be treated early.
Complication
Gallbladder carcinoid complications Complication
Individual patients have extrahepatic biliary obstruction due to excessive mass or proximity to the common bile duct.
Symptom
Gallbladder cancer symptoms Common symptoms Biliary obstruction jaundice bloating bloating loss of appetite gallbladder wall thinning
The disease lacks specific clinical manifestations. Most patients have a history of acute or chronic cholecystitis, which is characterized by swelling of the right upper quadrant, discomfort accompanied by oil disability, loss of appetite, etc. Individual patients are caused by excessive mass or close to the common bile duct. Extrahepatic biliary obstruction, causing obstructive jaundice or cholangitis, the incidence of carcinoid syndrome is low, accounting for about 7%.
Examine
Examination of gallbladder carcinoid
When biliary obstruction occurs, the blood bilirubin is elevated.
About 60% of patients with B-ultrasound can be found in the gallbladder with hypoechoic space-occupying lesions, generally less than 2cm in diameter.
Diagnosis
Diagnosis and diagnosis of gallbladder carcinoid
Diagnostic criteria
The disease has no specific clinical manifestations, preoperative diagnosis is difficult, imaging examination is the main means of finding this disease, B-ultrasound diagnosis is difficult to characterize, and the final diagnosis often needs to be determined by intraoperative or postoperative pathology.
1. Clinical manifestations.
2. Laboratory and other auxiliary inspections.
Differential diagnosis
The disease needs to be associated with gallbladder cholesterol polyps, cholecystitis polyps, adenomatous polyps, gallbladder gland hyperplasia and gallbladder cancer. B-ultrasound examination of cholesterol polyps often occurs, pedicle, strong echo, inflammatory polyp single Or multiple, often <1.0cm, medium echo, adenomatous polyps single or multiple, volume of 0.5 ~ 2.0cm, and gallbladder carcinoid is not easy to identify, gallbladder adenomyosis is a proliferative change of the gallbladder, characterized by Hyperplasia of the gallbladder mucosa muscle layer, angiography, there is a limited filling defect at the top of the gallbladder, but there is a contrast agent into the center, gallbladder cancer and this disease is difficult to identify.
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