Simple lentigo

Introduction to simple freckles Simple freckle-like sputum (simplelentigo) is a hereditary pigmentary skin disease with a high incidence of Caucasians and a low incidence in Asians. It begins to develop after receiving sun exposure, but it can only occur when it is 7 years old. Skin lesions occur on the face, neck, shoulders and back of the hand. Clinically characterized by scattered light brown or dark brown spots. May be associated with other systemic diseases and become part of certain hereditary syndromes. More clinical treatment is not needed, and freezing or laser treatment is better. basic knowledge The proportion of illness: 0.001% Susceptible people: no specific people Mode of infection: non-infectious Complications: pigmentation spots

Simple freckle-like cause

(1) Causes of the disease: The cause is unclear. Based on the disease, it is often associated with pigmented intestinal polyp syndrome and facial mesonosis. It is presumed that most of the disease is due to abnormal mutations in the development of neuroectoderm. There are defects in melanocyte function or abnormal melanin synthesis in the lesion.

(B) the pathogenesis: under light microscopy, the number of melanocytes in the basal layer of the epidermis is increased, but usually there is no focal hyperplasia or nesting distribution, melanin in melanocytes and basal keratinocytes is increased, and sometimes the upper layer of the epidermis is also visible. Melanin, the epidermis is mild to moderately prolonged, and there is often a small amount of inflammatory cell infiltration in the upper part of the dermis, mixed with melanocytes, occasionally small sputum nests in the epidermal dermis, and freckles-like ridges and junctions. Performance.

Simple freckle-like prevention

Avoid direct sunlight, do well in sun protection, and have a light diet.

Simple freckle-like complication Complications

The disease generally has no other complications. Due to the increase of melanin in the melanocytes and basal keratinocytes, persistent skin melanin deposition may occur, leading to skin pigmentation spots. However, most of the treatment with laser treatment or rubbing hydroquinone cream can alleviate. Secondly, because the disease is caused by sun exposure damage, strong ultraviolet rays can also cause skin burns and peeling, and should be distinguished.

Simple freckle-like symptoms common symptoms skin freckles

1. It can occur in the skin of any part of the body, at the junction of the skin and mucous membranes.

2. Brown spots: round, oval or irregular, flush with the skin surface or slightly bulging, ranging from light brown to dark brown, with clear boundaries, usually <5mm in diameter, smooth surface, and presence of skin lines. Single or multiple.

3. Incidence time: From childhood to adulthood, the number of lesions can be gradually increased, and it can also appear in abruptly diffusely in a short period of time. In the case of Addison disease, pregnancy and other diseases or conditions with increased MSH levels, the color of the lesion can be deepened. Can also increase significantly.

Simple freckle-like examination

Histopathology showed that the number of melanocytes in the basal layer of the epidermis increased, and the epidermal processes were mild to moderately prolonged.

Diagnosis and diagnosis of simple freckle-like sputum

Clinical diagnosis often requires pathological examination, because this disease can be seen in some hereditary syndromes, such as multiple freckle-like sputum syndrome, facial freckle-like rickets, perioral freckle-like rickets, LAMB syndrome, etc. Ignore the examination of other parts of the body to avoid missed diagnosis or misdiagnosis.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.