Leukemic angina
Introduction
Introduction to leukemia angina Leukemia is a malignant disease of hematopoietic tissue. Most patients often have pharyngeal lesions in the early stage, which is characterized by necrosis of the tonsils and pharyngeal isthmus. Often accompanied by irregular fever. Due to abnormal proliferation of leukocytes, a large number of abnormal leukemia cells can be produced, which are widely infiltrated into various tissues and organs in the body to produce different clinical manifestations. The body is exposed to cold, harmful gas pollution, high air dust rate, smoking and alcoholism, infectious diseases, kidney disease and blood diseases. Leukemia is a malignant disease of hematopoietic tissue. Most patients often have pharyngeal lesions in the early stages. Due to abnormal proliferation of leukocytes, a large number of abnormal leukemia cells can be produced, which are widely infiltrated into various tissues and organs in the body to produce different clinical manifestations. basic knowledge The proportion of illness: 0.0032% Susceptible people: no specific people Mode of infection: non-infectious Complications: ulcer bleeding
Cause
Causes of leukemia angina
Cause:
The body is exposed to cold, harmful gas pollution, high air dust rate, smoking and alcoholism, infectious diseases, kidney disease and blood diseases. Leukemia is a malignant disease of hematopoietic tissue. Most patients often have pharyngeal lesions in the early stages. Due to abnormal proliferation of leukocytes, a large number of abnormal leukemia cells can be produced, which are widely infiltrated into various tissues and organs in the body to produce different clinical manifestations.
Prevention
Leukemia angina prevention
1, pay attention to the impact of climate, especially in the autumn and winter seasons, the temperature changes drastically, should be timely added clothing, anti-virus invading the body and induced the disease.
2, to avoid exposure to certain toxic substances, including benzene hair dyes and other benzene-containing preparations, some drugs should be used with caution such as phenylbutazone, chloramphenicol, chloramphenicol, phenytoin, excellent pain, Kabbah lung.
3, during the treatment of leukemia, should maintain emotional stability, optimism, so that the body is in a good state, the so-called: "- gas in the deposit, evil can not do, mental internal specialization, illness and safety."
Complication
Complications of leukemia angina Complications ulcer disease bleeding
Secondary infection invades the mucosa, necrosis and ulceration appear in the submucosa and deep muscle layer, covered with gray-white pseudomembrane, and the tissue necrosis is brown and severe.
Symptom
Leukemia pharyngeal inflammatory symptoms common symptoms low fever chills secondary infection severe pain high fever bleeding tendency
When acute leukemia begins, there are often irregular fevers, followed by high fever, chills, and the general condition turns sharply downwards. Symptoms of poisoning and circulatory failure occur quickly, such as poor physical condition, no fever, only low fever.
Pharyngeal mucosal edema, pale, pharyngeal wall, tonsil and soft palate with blood stasis or ecchymosis, secondary infection invading the mucosa, submucosa and deep muscle layer necrosis and ulceration, covered with gray-white pseudomembrane, severe tissue necrosis The area is brown and has a tendency to hemorrhage. There is no inflammatory swelling in the tonsil and the base of the tongue. In the early stage of acute leukemia, there is often no painful lymphadenopathy in various parts of the body. Pharyngeal ulceration can cause severe pain and difficulty swallowing. Bad breath and sometimes symptoms such as restricted mouth opening.
Examine
Examination of leukemia angina
1, blood: white blood cells are always significantly increased (or reduced), can appear primitive or immature cells.
2, bone marrow: bone marrow nucleated red blood cells accounted for less than 50% of all nuclear cells, primordial cells 30%, can be diagnosed as acute leukemia; such as bone marrow nucleated red blood cells 50%, the proportion of primordial cells in non-erythroid cells 30 % can be diagnosed as acute erythroleukemia.
Diagnosis
Diagnosis and diagnosis of leukemia angina
diagnosis
Rapid onset, leukemia symptoms, signs and history, typical tissue necrotic manifestations of the pharynx and remarks see leukocyte proliferation, primordial cells and naive cells, these changes are more pronounced in the bone marrow.
Differential diagnosis
The disease needs to be differentiated from the following diseases:
1, pharyngeal malignant granuloma usually slow onset, early general condition is good, pharyngeal ulceration, but the pain is not obvious, the necrotic site is mostly in the midline position, can be identified.
2. Aplastic anemia.
3. Myelodysplastic syndrome.
4. Malignant histiocytosis.
5, idiopathic thrombocytopenic purpura needs to be identified.
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