Strychnine poisoning

Introduction to Shi Ning's poisoning Strychnine (mazanine, saponin) is an alkaloid extracted from the scorpion (Panmu), which can selectively excite the spinal cord and enhance the tension of skeletal muscle. Or the treatment of amblyopia, commonly used is nicotine nitrate. Strychnine is a central nervous system stimulant with a small therapeutic safety range and is rarely used clinically. Strychinine poisoning is mostly caused by overdose of medical drugs or misuse of the seeds of Strychnos chinensis and the poisonous rodenticide containing Shi Ning. When entering the body in excess, symptoms can appear in 10 to 30 minutes, the main feature is the generalized tonic spasm. Children are more sensitive to this product, prone to poisoning, showing a variety of central nervous system symptoms. basic knowledge The proportion of illness: 0.001% Susceptible people: no special people Mode of infection: non-infectious Complications: hand and foot cyanosis

The cause of Shi Ning's poisoning

Cause:

Poisoning many groups accidentally took a lot of money. Shi Ning Yi is absorbed from the digestive tract and the injection site, and is mainly detoxified in the liver after entering the body. Some of the poisons accumulated in the liver and muscle tissue, can be released into the blood again, leading to secondary poisoning. A part of the body is discharged from the urine in its original form, and it is generally discharged within 10 hours. It can selectively fight glycine, relieve the post-synaptic inhibition process of the central nervous system, and eliminate the inhibition between neurons.

Shi Ning poisoning prevention

Should be avoided as much as possible, the application must be strictly controlled, the child should be used with caution or disabled. Take care of children and prevent accidental consumption of poisons and drugs. Adolescents can develop a self-injury drug health search and pay attention to the physical and mental health problems of adolescents. Strengthen publicity and popularize related anti-drug knowledge such as botanical drugs. It is not advisable to prevent this medicine for newborns and babies. Patients with anemia, heart, lung, kidney, and liver disease are contraindicated for repeated use of this drug for a long time.

Sinning poisoning complications Complications of the foot and the foot

Respiratory muscles, diaphragmatic spasm, respiratory arrest in the maximum inspiratory state, resulting in suffocation, cyanosis, in addition, a small number of patients may have photophobia, painful urinary leaching, myalgia and other complications.

Shi Ning poisoning symptoms common symptoms twitching horn bow anti-tension smile face irritability convulsions conscious loss

Shi Ning is a central nervous system stimulant. When it enters the body, it initially shows irritability, rapid movement, stiffness of the facial muscles and neck muscles, narrowing of the pupils; or excessive sensitivity to sight, hearing, taste, touch, etc. Dilated pupils, tachycardia, whole body tremors, convulsions, convulsions, etc., convulsions first appear clonic, then turn into tonicity, sick children have horned arches, bitter smile face, due to respiratory muscle spasm contraction, often Caused by suffocation and cyanosis, any stimulation can cause recurrence of seizures. Severely poisoned children can die due to respiratory paralysis, circulatory failure, asphyxia, etc. Most cases are always clear, and a few sudden consciousness loss, showing a coma.

Inspection of Shi Ning poisoning

1. Toxic substances, urine, and blood can be analyzed for toxicant concentrations.

2. Blood concentration determination The poisoning blood concentration is 2 mg/L, and the lethal blood drug concentration is 9-12 mg/L.

3. Laboratory toxicology analysis.

4. Take the gastric juice residue and add 1 drop of concentrated sulfuric acid. After dissolving, put 1 small potassium dichromate crystal, which immediately appears blue or purple blue, and quickly turns orange-red, which confirms the diagnosis.

5. Take 1ml of gastric lavage fluid and inject into the lymphatic sac of the strong frog. If the frog's hind legs are strong and straight after several minutes to half an hour, the diagnosis can be confirmed.

Diagnosis and identification of Shi Ning poisoning

diagnosis

Diagnosis can be based on medical history, clinical symptoms, and laboratory findings.

Differential diagnosis

It is differentiated from other central stimulant poisoning, such as lycopene, nikethamide, caffeine, camphor and other drug poisoning.

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