Urinary pepsinogen

Pepsinogen is secreted by the main cells of the gastric gland and activated by the action of hydrochloric acid to become a pepsin having a hydrolyzed protein action. In human gastric juice, pepsin hydrolyzes proteins into purines, small amounts of amino acids (tyrosine, phenylalanine), and polypeptides. Electrophoresis analysis can be used to divide the pepsinogen produced by human gastric mucosa into seven groups, which can be divided into two groups by immunology. Pepsinogens 1 to 5 are group I, and groups 6 to 7 are group II. Group I was found only in the fundus and corpus callosum. Group II was found in the pyloric gland and duodenal mucosa in addition to the fundus and corpus callosum. Both are present in the blood, but only pepsinogen I in the urine is activated into a urine (stomach) protease under weak urine conditions. Basic Information Specialist classification: growth and development check classification: urine / kidney function test Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Gastric cancer, megaloblastic anemia (malignant anemia), hypopituitarism, hypothyroidism (mucinous edema), gastric resection. Normal value: Urinary pepsinogen (enzymatic method): 130-930Miu/24h Above normal: Duodenal ulcer, hyperthyroidism, Cushing's syndrome (adrenal hyperfunction). negative: Positive: Tips: Try to use fresh morning urine when doing this check. The urine that is randomly selected is preferably mid-stage urine. Menstrual women are not suitable for this examination. Normal value Enzymatic method (37 ° C) 130 ~ 930Miu / 24h. Clinical significance Abnormal results: Increase duodenal ulcer, hyperthyroidism, Cushing's syndrome (adrenal hyperfunction). Reduce gastric cancer, megaloblastic anemia (malignant anemia), hypopituitarism, hypothyroidism (mucinous edema), gastric resection. The people who need to be examined have abdominal pain, fatigue, weakness, fear of hot and sweaty, damp skin, eating more hunger, and significantly declining weight. Low results may be diseases: high hypothyroidism may result in diseases: precautions for hyperthyroidism in the elderly Note during inspection: Fresh morning urine should be used as much as possible during this examination. The urine that is randomly selected is preferably mid-stage urine. Not suitable for the crowd: menstrual women. Inspection process Inspection process: As with routine urine tests, use a clean, dry container with a disposable urine cup and urine test tube provided by the hospital. Take about 10 ml of urine and send it to the designated inspection window of the hospital, and then use the antibody method to detect it. Not suitable for the crowd Menstrual women. Adverse reactions and risks no.

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