Urinary testosterone

Testosterone is the main androgen in the human body. 95% of adult male plasma testosterone comes from Leydig cells, and a small part comes from adrenal cortex and extra-glandular transformation. Women are mainly from the adrenal cortex, and the ovaries secrete a small amount. Most of the testosterone in the plasma binds to the beta globulin of the testosterone-binding protein, and only a very small amount is in a free state to exert a physiological effect. Testosterone promotes the synthesis of proteins and bone matrix and increases the production of erythropoietin. Testosterone is the main indicator of androgen. Basic Information Specialist classification: growth and development check classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Tips: Stop taking barbiturate sedatives, clomiphene citrate, gonadotropins and oral contraceptives. The middle part of the urine is taken for inspection. Normal value Urine male 175 ~ 472nmol / 24h (50 ~ 135μg / 24h); Female 7 ~ 42nmol / 24h (2 ~ 12μg / 24h); >50 years old male 140 ~ 210nmol / 24h (40 ~ 60μg / 24h); Female 7 ~ 28nmol / 24h (2 ~ 8μg / 24h). Clinical significance Abnormal result (1) rise 1 male A. Metabolic hyperthyroidism. B. Tumor testicular stromal cell tumor. C. Drug-induced LH-RH?hcG. 2 women A. Ovarian polycystic ovary syndrome, testicular cell malignant tumors, etc. B. Adrenal 21-hydroxylase deficiency, 11β-hydroxylase deficiency. Cushing's syndrome, masculine adrenal tumors, etc. C. Idiopathic hirsutism. D. Congenital ovarian hypoplasia (Turner syndrome). E. Hyperthyroidism. F. Pregnancy. G. Use ACTH. (2) lower 1 male A. Leydig cell deficiencies. B. Delayed puberty Low gonadotropin insufficiency, Prader-Willi syndrome (low muscle tone - low intelligence - sexual development low - obesity syndrome). C. Abnormal enzymes related to androgen synthesis 3β-hydroxylated steroid dehydrogenase deficiency, 17-hydroxylase deficiency, 17,20-hydroxylase deficiency, 17β-hydroxylase deficiency. D. Congenital testicular hypoplasia (testicular dysplasia) hereditary myotonia, primary testicular damage, XX-positive (male) testicular excision in the elderly. E. Hyperprolactinemia. F. Metabolic cirrhosis, chronic renal insufficiency. G. Cushing syndrome. H. Estrogen produces a tumor (adrenal gland). I. Drug ACTH, estrogen, synthetic androgen, and the like. J. Dialysis. 2 women A. Adrenal insufficiency Primary adrenal insufficiency (Addison's disease), Sheen syndrome (postpartum pituitary dysfunction). B. Insufficiency of the anterior pituitary. People who need to be tested Eat more, lose weight, eye protrusion, goiter, hypothyroidism. Low results may be diseases: Sheen syndrome results are high may be diseases: hyperthyroidism, polycystic ovary syndrome precautions Before the test: Stop taking the barbiturate sedative, clomiphene citrate, gonadotropin and oral contraceptives. At the time of examination: a part of the urine is discharged first to wash away the bacteria remaining in the urethra and the anterior urethra, and then the middle part of the urine is taken for examination. Inspection process The urine of the subject is collected and detected by chemical methods. Not suitable for the crowd Not suitable for people: cold patients. Adverse reactions and risks No.

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