Cryptococcosis latex agglutination test

Latex agglutination test for detection of Cryptococcus neoformans capsular polysaccharide antigen is a simple, rapid and effective laboratory method for the diagnosis of cryptococcal infection. It uses latex particles as a carrier and is attached with anti-Cryptococcus neoformans antibodies to form a sensitizing latex suspension. For example, specimens (serum, pleural effusion, bronchoalveolar lavage or cerebrospinal fluid) contain a certain amount of cryptococcal capsular polysaccharide. The antigen produces macroscopic agglutination particles. There is no definite diagnostic threshold for this test, and its sensitivity and specificity remain to be verified, but it provides useful clues for early diagnosis of pulmonary cryptococcosis. Basic Information Specialist classification: Respiratory examination classification: sputum examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Cryptococcus neoformans infection (central nervous system and systemic). Tips: Cross-reaction with rheumatoid latex agglutination test. Normal value negative. Clinical significance Positive: Cryptococcus neoformans infection (central nervous system and systemic). Positive results may be diseases: pulmonary cryptococcosis, new cryptococcal meningitis considerations This test is easy to cross-react with the rheumatoid latex agglutination test and must be excluded. Inspection process Agglutination test. Not suitable for the crowd People with reduced hematopoietic function such as leukemia, various anemia, myelodysplastic syndrome, or people with thrombocytopenia should pay attention to blood draw, and should not take more or more blood. Adverse reactions and risks 1. After the blood is drawn, do not press the needle hole to avoid subcutaneous hematoma. If there is a small piece of bruise in the blood, it is slightly tender, please don't panic, you can do hot compress after 24 hours to promote the absorption of blood. The general small amount of congestion will gradually absorb in 3 to 5 days and the color will become lighter and return to normal. 2. After the blood draw, symptoms such as dizziness, vertigo, fatigue, etc. should be immediately supine, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved.

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