pre-S antibody

Since the pre-S protein is more immunogenic than HBsAg, pre-S antibodies appear soon after the appearance of the pre-S protein. Therefore, the pre-S antibody is the earliest antibody in the presence of HBV infection, and reaches a high peak after anti-Hbe seroconversion, but it has a short duration, and generally lasts only about 6 to 12 months in the recovery period of acute infection, often with Other antigens are present at the same time. Unlike anti-HBs, which prevent viral reinfection by neutralization, pre-S antibodies clear the virus by destroying infected cells, and thus participate in the activity of the lesion and the immune clearance mechanism. Basic Information Specialist classification: Digestive examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: A positive pre-S antibody indicates that the virus is or has been cleared, suggesting a good prognosis; if the pre-S antibody is delayed, it means a poor prognosis. Tips: After 8 pm on the day before the medical examination, you should start fasting for 12 hours, so as not to affect the test results. Normal value negative. Clinical significance (1) Positive S antibody indicates that the virus is or has been cleared, indicating a good prognosis; if the pre-S antibody is delayed, it means a poor prognosis. (2) If there is a pre-S antibody in patients with acute severe hepatitis, it indicates a certain degree of vitality to a certain extent. (3) The pre-S1 protein can activate T cells, so the production of other antibodies can play an adjuvant-like role. Positive results may be diseases: hepatitis, hepatitis D virus hepatitis precautions Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Inspection method: draw blood. Not suitable for the crowd There are no special taboos. Adverse reactions and risks There are no related complications and hazards.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.

Was this article helpful? Thanks for the feedback. Thanks for the feedback.