Basal gastric secretion/maximum gastric acid output
There are various methods for examining the secretion of gastric acid, such as the basic gastric acid secretion test without giving any stimulating agent. The stimulating agent is used to directly or indirectly stimulate the secretory cells of the gastric mucosa to observe its secretory function, such as the pentagastrin gastrin test. In addition, through the stimulation of the vagus nerve, the observation of gastric secretion function, such as insulin-stimulated gastric secretion test, is selected according to clinical needs. The test can still be affected by the patient's gender, spirit, age, appetite, and alcohol hobby. Therefore, the determination of gastric acid secretion is less specific for the diagnosis of diseases, and only has a certain significance in the diagnosis of duodenal ulcer, gastrinoma, gastric cancer and the like. Basic Information Specialist classification: Digestive examination classification: body fluid examination Applicable gender: whether men and women apply fasting: fasting Tips: 24 hours before the test, use all drugs that can affect the secretion of gastric juice, fasting for 12h. Then, the stomach juice on the fasting morning was discarded, and all the gastric juice in 1 hour was collected continuously, and the amount was recorded in a small bottle and sent for inspection. Normal value According to MAO, normal males were 18.02±8.84 mmo1/hour, and females were 13.43±7.98 mmo1/hour. Clinical significance Abnormal results: gastrinoma BAO>15mmol/L, MAO>30mmol/L, BAO/MAO>0.6. People in need of examination: abnormal symptoms appear in the stomach. Precautions Before the test: 24 hours before the test, use all drugs that can affect the secretion of gastric juice, fasting for 12h. Then, the stomach juice on the fasting morning was discarded, and all the gastric juice in 1 hour was collected continuously, and the amount was recorded in a small bottle and sent for inspection. At the time of examination: after the BAO specimen was taken, MAO was intramuscularly injected with pentagastrin gastrin. The dose was calculated according to the weight of 6μg/kg body weight. A sample was collected every 15 minutes for 4 times and sent to the bottle with 4 partial marks. . Inspection process (1) On the day before the analysis of gastric juice, various drugs that affect the secretion of gastric juice, such as atropine and probensin, were stopped. Fasted for 12 hours after dinner on the previous day. (2) Checking the stomach in the morning on the morning, inserting the stomach tube from the nostrils, when the stomach tube is inserted into the pharyngeal gorge, there is often a feeling. At this time, the patient should take the active spring pharyngeal movement, and the operator will insert the stomach tube into the esophagus. If you have a sense of care through the pharyngeal gorge, deep breathing can be alleviated. When the stomach tube enters the esophagus and enters a length of about 56 cm, the gastric juice can be withdrawn, indicating that it has reached the stomach cavity. If the nasal cavity has a disease that cannot be inserted, it can also be inserted through the mouth. (3) Drain the fasting gastric juice. Then, the gastric juice was continuously extracted for 1 hour, the gastric juice was kept in the container, and the gastric acid was measured and measured. The gastric juice is usually taken once every 15 minutes for 4 times. The sum of gastric acid is called the amount of basal gastric acid secretion, expressed as BAO. The normal value is less than 5mmo1/hour. (4) Use a stimulant such as subcutaneous injection of histamine or subcutaneous injection of five gastrin. The gastric juice was then continuously aspirated, and the gastric juice was collected once every 15 minutes for 4 times. After the injection of the gastric acid stimulating agent, the total amount of gastric acid secretion collected four times in one hour is called the maximum gastric acid excretion. According to MAO, normal males were 18.02±8.84 mmo1/hour, and females were 13.43±7.98 mmo1/hour. The highest gastric acid output in two consecutive 15 minutes in 4 specimens was multiplied by 2, which is called the peak acid output, expressed as PAO. According to the application of stimulants can be divided into: 1 histamine test: subcutaneous injection of histamine phosphate 40 μg / kg body weight. 2 five gastrin test: the injection dose is 6 micrograms / kg body weight. Previously, a trial test was used, such as eating half a taro or two slices of bread and 400 ml of warm boiled water. Therefore, the method is not accurate and is not used now. (5) Inspection: The gastric juices taken at different times are examined, including general traits (color, taste, etc.), gastric acid determination, occult blood test, bacterial detection, and various cell analysis such as tumor cells. Not suitable for the crowd Not suitable for the crowd: no. Adverse reactions and risks There are no related complications and hazards.
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