Serum aspartate aminotransferase to serum aspartate-alanine aminotransferase ratio

There is no enzyme test that is specific for the diagnosis of liver disease. In other words, it is impossible to confirm the diagnosis based on the test results of only one enzyme. Therefore, it is necessary to combine the determination of the enzymes and perform a comprehensive analysis, that is, to determine the value of the enzyme detection by measuring the relationship of various enzymes, thereby providing observation. The ratio of enzymes to assist in the diagnosis of liver disease is more clinically significant. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: fasting Tips: Before the examination, the diet is light and alcohol is prohibited. Check for an empty stomach in the morning. Normal value The normal ratio of SGOT/SGPT is about 1:1. Clinical significance The AST/ALT ratio decreases, which is common in acute hepatitis and mild hepatitis. The recovery rate of hepatitis has gradually increased. The AST/ALT ratio is elevated, and fulminant hepatitis is predicted in acute conditions. The ratio of chronic liver disease increased in the order of chronic persistent hepatitis, chronic active hepatitis, cirrhosis, and liver cancer. High results may be diseases: liver cancer, cirrhosis, fulminant hepatitis-like syndrome, chronic hepatitis precautions (1) Uremia and dialysis patients, vitamin B6 deficiency, diabetic ketosis, acidosis, malaria, pregnancy, etc. are low values. (2) HBV asymptomatic carriers, idiopathic portal hypertension, etc. are in the normal range. Inspection process Immediately after venous blood collection, the test is performed. (1) Colorimetric method: With the ALT colorimetric assay, only the enzymatic reaction time was changed to 60 min, and the AST standard curve was checked. (2) Continuous monitoring method: The analysis conditions should be determined according to the specifications of the instrument of this laboratory. Main parameters: same as ALT continuous monitoring method. Not suitable for the crowd Generally there are no special taboos. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.

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