estrogen withdrawal test
The estrogen withdrawal test is an examination performed when progesterone fails to cause withdrawal bleeding. The objective is to give the patient a sufficient amount of estrogen and progesterone to observe the bleeding after stopping the drug. Sexual intercourse was prohibited for the first three days of the examination. After 8 pm on the day before the medical examination, you should fast. The examination should be 3-7 days after the menstrual cleansing. Basic Information Specialist classification: gynecological examination classification: blood examination Applicable gender: whether women are fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Negative reactions should be normal. Positive: It is suggested that the endometrium is defective or has been damaged. Tips: Forbidden sex is prohibited for the first three days of the examination. After 8:00 pm on the day before the medical examination, you should fast. Normal value The result of the test was negative. Clinical significance Abnormal result 2 to 7 days after stopping the drug, the bleeding was positive, indicating that the patient has a normal function of the endometrium, and the foreign female and progesterone can respond, which proves that amenorrhea is due to the lack of estrogen in the body, called II degree. amenorrhea. If there is no withdrawal bleeding after stopping the drug, an estrogen test can be repeated to induce the production of estrogen receptors in the endometrium. If there is still no bleeding, suggesting that the endometrium is defective or has been destroyed, it is called uterine amenorrhea. People who need to be examined have people with amenorrhea symptoms. Positive results may be diseases: premature ovarian failure, uterine infertility precautions Inappropriate population: Those who did not undergo a progesterone withdrawal bleeding test. Pre-inspection contraindications: sexual intercourse is prohibited for the first three days of the examination. After 8 pm on the day before the medical examination, you should fast. The examination should be 3-7 days after the menstrual cleansing. Estrogen is responsible for the development of the uterus, vulva, and breast. If the development is poor, the estrogen should be stimulated. It should be carried out before the age of 20, but the effect is not good. Requirements for inspection: Checking for relaxation, checking may cause physical and psychological burdens, should be actively faced, and actively cooperate with the inspection. In the second half of the menstrual cycle, estrogen should retreat to the supporting role, and let progesterone play a leading role. Otherwise, premenstrual syndrome can occur, such as acute phlegm, edema, dry mouth, palpitations, bloating, insomnia, depression, bloating, etc., before and after the treatment. This is caused by high estrogen, and the symptoms are not heavy and there is no need to treat it. Inspection process Oral diethylstilbestrol, 1mg daily, for 20 days; or ethinyl estradiol, 0.05mg daily, for 20 days. On the 16th day of taking the drug, daily intramuscular injection of 20 mg of progesterone or oral administration of 10 mg of progesterone daily for 5 days. Observe the bleeding after stopping the drug. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.
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