Platelet Adhesion Test

Platelet adhesion refers to the adhesion of platelets to the surface of foreign bodies and is an important hemostatic function of platelets. The results are elevated in hypercoagulable states and thrombotic diseases such as myocardial infarction, angina pectoris, cerebrovascular disease, diabetes, deep vein thrombosis, glomerulonephritis and pregnancy-induced hypertension syndrome. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: It is not advisable to take aspirin within the first 10 days of the test. Normal value 1. Glass ball method, male: 34.9%±6.0%; female: 39.4%±5.2%. 2, glass bead column method: 62.5% ± 86%. 3. The glass filter method is 31.9%±10.9%. Clinical significance The platelet adhesion test reflects the adhesion function of platelets. The results are elevated in hypercoagulable states and thrombotic diseases such as myocardial infarction, angina pectoris, cerebrovascular disease, diabetes, deep vein thrombosis, glomerulonephritis and pregnancy-induced hypertension syndrome. The results were reduced in von Willebrand disease, giant platelet syndrome, and cirrhosis, uremia, myelodysplastic syndrome, taking platelet-suppressing drugs, and eating fish oil. In particular, it is not advisable to take aspirin within 10 days of the test. Precautions First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the physical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. If you have a history of fainting, please explain in advance and make special arrangements. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process (1) Glass ball method: 1 Take 4.5ml of venous blood, place it in a centrifuge tube containing 0.129mol/L sodium citrate solution 0.5ml, and mix gently. 2 Immediately take 1.5ml of blood sample with a micro-injector, place it in a spherical bottle, place the spherical bottle on the rotating device, and rotate it at a speed of 3r/min for 15min to make the blood fully contact with the bottle wall. 3 Then use the two micro-most syringes to accurately absorb 1.0ml of blood from the centrifuge tube (before contact) and the spherical bottle (after contact), respectively, in two large test tubes, and then add 0.109mol/L each. 19 ml of sodium acetate solution, covered with a plastic film, repeatedly poured 3 times, mixed, and placed at room temperature for 2 h. 4 Take the supernatant to accurately count the platelets. (2) Glass bead column method: 1 Connect the ends of the bead column to the needle and syringe, respectively. 2 lines of elbow vein puncture. 3 When the blood contacts the bead column, immediately start the stopwatch and master the speed of the blood passing through the bead column. In the four-part bead column, the blood passes through each segment for 5s for 20s. 4 Then pump for another 6 to 7 seconds at the same speed, then pull out the needle. 5 Collect the blood in the plastic tube before and after the glass bead column, and make platelet counts respectively. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.

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