Whole blood selenium

The total amount of selenium in adults is 14-21 mg. After selenium absorbed from the intestine enters the plasma, it is mainly transported to the whole body tissue in combination with blood globulin and lipoprotein. It is mainly stored in liver, kidney, spleen, lung, heart muscle and blood, and about 1/3 of selenium is present in glutathione peroxidase. Its content is rarely discharged before it is saturated in the body. Excess selenium entering the body can be converted from exhaled excretion in the liver by conversion to volatile dimethyl selenium. The main route of selenium is still urine. The physiological function of selenium in the body is to maintain the normal metabolism of the heart muscle. As a natural antidote to natural antioxidants and heavy metals in the body, selenium is also related to immunity. Chronic selenium deficiency in humans is also closely related to the occurrence of diseases such as cancer, cardiovascular disease, and endemic cardiomyopathy (Keshan disease). Basic Information Specialist classification: growth and development check classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: Serum level determination is mostly used for nutritional investigation and toxicological analysis. Normal value Spectrophotometry (AAS) 1.27 to 2.4 μmol/L (10 to 18.9 μg/dl). Clinical significance (1) Reduce Keshan disease, cardiomyopathy, coronary heart disease, myocardial infarction, high nutrition of veins, etc. (2) Increase selenium poisoning (up to 4 times higher than normal). Low results may be diseases: high results of coronary heart disease may be diseases: precautions for skin diseases caused by selenium and its compounds Serum level determination is mostly used for nutritional investigation and toxicological analysis. Inspection process Determination of ionic selenium: The selenium electrode used in the commercial ion selenium analyzer uses a neutral carrier as the active material of the selenium electrode to form a polyvinyl chloride (PVC) electrode film. The life of the electrode is about half a year: the pH electrode is made of special glass capillary The reference electrode is made of silver/silver chloride. The reagent formulations, reagent dosages, and operation methods of various types of ionic selenium analyzers are different. Generally, the following steps are required. This method takes a domestic ion selenium analyzer as an example. 1 Connect the power supply, the instrument first performs display and electronic circuit detection, and the two-point slope calibration can be performed after the end. 2 When the slope is calibrated, the suction needle is immersed in the vial containing the low and high two-concentration slope calibration instrument, and the slope calibration solution is taken up, and the instrument is sent after the “beep” sound is removed. The sample is pushed back to the original position and the instrument automatically performs the slope calibration. 3 After the calibration is passed, the sample measurement can be performed. A. Capillary blood measurement: Mix the capillary blood, push out the aspirating needle, remove the plug at both ends, attach the connector at one end, mount the other end of the connector on the sampling needle, and press the “Measure” button until the sample is completely filled with the sample. After the cavity, release the “Measure” button and the sample pump stops working. At this time, the sample in the sample measuring chamber should be inspected for bubbles. If there are air bubbles, please release the “Measure” button for 8 seconds, then press the “Measure” button to continue to suck the sample until the bubbles are eliminated. Remove the sample, wipe the sample and push it back in place, and display the measurement data and print the result after 8 s of the injection. B. Serum measurement process is measured with whole blood. 4 After the specimen is measured, the instrument is flushed with the pipeline and the sample is measured. After the rinse is completed, the next sample can be measured. 5 The instrument will enter the “sleep” state after 10 minutes of the last calibration or blood sample measurement. At this time, if blood sample measurement is required, a certain calibration must be performed first. If there is no blood sample measurement, the instrument automatically performs a one-point calibration every 30 minutes. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.

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