squamous cell carcinoma antigen

Squamous cell carcinoma antigen is a glycoprotein isolated from cervical squamous cell carcinoma and is present in the cytoplasm of squamous cell carcinoma cells such as uterus, cervix, esophagus, lung, head and neck. A highly specific squamous cell tumor marker with low sensitivity. The concentration of squamous cell carcinoma-associated antigen increases with the severity of the disease, and can be used as an auxiliary diagnostic index for cervical cancer, lung cancer, head and neck cancer, and a monitoring index for efficacy, recurrence, and metastasis. Basic Information Specialist classification: Oncology examination classification: immune examination Applicable gender: whether men and women apply fasting: not fasting Tips: After taking venous blood (no need for fasting), serum (at least 0.5ml) should be separated as soon as possible. Normal value ≤10μg/L. Clinical significance Elevation is common in cervical cancer, lung cancer, head and neck cancer. In addition, hepatitis, cirrhosis, pneumonia, renal failure, tuberculosis and other diseases will also increase to some extent. Squamous cell carcinoma antigens were first used to diagnose squamous cell carcinoma. In cervical cancer, lung cancer, head and neck cancer, the serum squamous cell carcinoma antigen is increased, and its concentration increases with the severity of the disease. Determination of squamous cell carcinoma antigens can monitor the efficacy, recurrence, metastasis and prognosis of these tumors. The detection rate of lung cancer only accounted for 28.6%, but the detection rate of lung squamous cell carcinoma can account for 44.4%. Combined detection with CYFRA-21-1 can increase the positive rate. High results may be diseases: squamous cell carcinoma, cervical cancer, cervical invasive cancer, lung cancer Contraindications before inspection: This inspection should be carried out as early as possible, and pay attention to the appointment in advance. Requirements for examination: After venous blood is drawn (no fasting is required), serum (at least 0.5 ml) should be separated as soon as possible. If the test cannot be performed on the day, the serum should be separated from the whole blood and stored in a refrigerator at -20 ° C or -80 ° C. Reconstitute and shake well. Inspection process Detection operation: The ELISA is tested with serum. First, the blood is agglutinated for at least half an hour, and then serum is taken. After diluting the enzyme complex with the diluent, add serum and a negative, positive control, and a control (this is a strict requirement, and its range must be within the control range). After an hour of incubation, then wash the plate, add the substrate, half an hour to avoid the light reaction and add the stop solution to complete the reaction part, then the reading. The result is judged to be negative or positive by the value. Not suitable for the crowd Those without examination indications should not be tested. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.

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