Serum α2-macroglobulin (α2-MG)
α2-MG is the largest molecular weight protein in plasma and is synthesized by hepatocytes and mononuclear-macrophage systems. The half-life is about 5 days and has the effect of an enzyme inhibitor. It can regulate extracellular proteolysis and stimulate lymphocyte and granulocyte development. Determination of α2-macroglobulin in the blood has a certain significance for the diagnosis of liver and kidney diseases. Basic Information Specialist classification: urinary examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Reduced in emphysema, chronic hepatitis, diabetes, hyperthyroidism, acute glomerulonephritis, acute pancreatitis, disseminated intravascular coagulation (DIC), malnutrition. Normal value: Male: 1.50-3.50g/L Female: 1.75-4.70g/L Above normal: Elevation is seen in nephrotic syndrome, cirrhosis, diabetes, acute and chronic hepatitis. negative: Positive: Tips: pregnant women, women with oral contraceptives, estrogen drugs, can also see elevated alpha 2 macroglobulin. Normal value Immunodiffusion method (RID method) Male 1.50 ~ 3.50g / L (150 ~ 350mg / dl). Female 1.75 ~ 4.70g / L (175 ~ 470mg / dl). Clinical significance 1, elevated in nephrotic syndrome, cirrhosis, diabetes, acute and chronic hepatitis. 2, reduced in emphysema, chronic hepatitis, diabetes, hyperthyroidism, acute glomerulonephritis, acute pancreatitis, disseminated intravascular coagulation (DIC), malnutrition. Low results may be diseases: liver cirrhosis, chronic hepatitis results may be high disease: acute glomerulonephritis, acute pancreatitis, emphysema precautions Pregnancy, oral contraceptive women, estrogen drug treatment, also seen elevated α2 macroglobulin. Inspection process Immediately after venous blood collection, the test method is the same as the RID measurement (immuno diffusion method). Not suitable for the crowd no. Adverse reactions and risks no.
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