semen acid phosphatase

ACP is present in all tissues of the body and is most abundant in the prostate. In normal male serum, 2/3 of ACP is from the prostate. Almost all ACP in seminal plasma comes from the prostate. Therefore, the determination of ACP in seminal plasma helps to understand prostate function and diagnosis of prostate disease. Basic Information Specialist classification: male examination check classification: semen and prostatic fluid examination Applicable gender: whether the male is fasting: not fasting Analysis results: Below normal: prostatitis. Normal value: Semen acid phosphatase: 48.8-208.6U/ml Above normal: Prostate cancer and enlarged prostate. negative: Positive: Tips: You need to abstain from sex for 3-7 days before the test. It is recommended to avoid drinking and overwork in the near future. Normal value 48.8 ~ 208.6U / ml. Clinical significance 1. ACP activity is reduced during prostatitis. 2, A prostate activity can be increased when prostate cancer and prostatic hypertrophy. 3. ACP has the role of promoting sperm activity. The ACP in the seminal plasma is reduced, and the sperm motility is weakened, which can reduce the fertilization rate. Low results may be diseases: high prostate cancer results may be diseases: prostatitis, benign prostatic hyperplasia 1. The activity of acid phosphatase in red blood cells is about 100 times higher than that in serum, so the specimen is not soluble in blood. Formaldehyde can inhibit acid phosphatase activity in red blood cells, but prostatic acid phosphatase is not affected, so if 37% to 40% formaldehyde is added (treated in buffer-matrix mixture), if acid phosphatase is still high, it means This acid phosphatase may be derived from the prostate (formaldehyde method: take 1% of commercially available 37% to 40% formaldehyde 50ml plus phenolphthalein indicator, and then add 0.1mol/L sodium hydroxide solution until red color appears). 2, the acid phosphatase of the prostate is not heat-resistant, the serum is placed at 37 ° C for 1 h, the activity of the enzyme is almost completely disappeared, so the specimen should be processed in time, otherwise it should be stored in the refrigerator. Inspection process Use the sodium phenyl phosphate process. Not suitable for the crowd no. Adverse reactions and risks no.

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